A flexible brace maintains the assembly of a hexameric replicative helicase during DNA unwinding

The mechanism of DNA translocation by papillomavirus E1 and polyomavirus LTag hexameric helicases involves consecutive remodelling of subunit–subunit interactions around the hexameric ring. Our biochemical analysis of E1 helicase demonstrates that a 26-residue C-terminal segment is critical for main...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Whelan, Fiona, Stead, Jonathan A., Shkumatov, Alexander V., Svergun, Dmitri I., Sanders, Cyril M., Antson, Alfred A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2012
Gaiak:
Structural Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3300016/
https://ncbi.nlm.nih.gov/pubmed/22067453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr906
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