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The mechanism of DNA unwinding by the eukaryotic replicative helicase
Accurate DNA replication is tightly regulated in eukaryotes to ensure genome stability during cell division and is performed by the multi-protein replisome. At the core an AAA+ hetero-hexameric complex, Mcm2-7, together with GINS and Cdc45 form the active replicative helicase Cdc45/Mcm2-7/GINS (CMG)...
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| Published in: | Nat Commun |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group UK
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6517413/ https://ncbi.nlm.nih.gov/pubmed/31089141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09896-2 |
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