Structural basis for DNA strand separation by a hexameric replicative helicase

Hexameric helicases are processive DNA unwinding machines but how they engage with a replication fork during unwinding is unknown. Using electron microscopy and single particle analysis we determined structures of the intact hexameric helicase E1 from papillomavirus and two complexes of E1 bound to...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Chaban, Yuriy, Stead, Jonathan A., Ryzhenkova, Ksenia, Whelan, Fiona, Lamber, Ekaterina P., Antson, Alfred, Sanders, Cyril M., Orlova, Elena V.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2015
Aiheet:
Structural Biology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4787811/
https://ncbi.nlm.nih.gov/pubmed/26240379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv778
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