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Structural basis for DNA strand separation by a hexameric replicative helicase
Hexameric helicases are processive DNA unwinding machines but how they engage with a replication fork during unwinding is unknown. Using electron microscopy and single particle analysis we determined structures of the intact hexameric helicase E1 from papillomavirus and two complexes of E1 bound to...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4787811/ https://ncbi.nlm.nih.gov/pubmed/26240379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv778 |
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