YB-1, an abundant core mRNA-binding protein, has the capacity to form an RNA nucleoprotein filament: a structural analysis

The structural rearrangements accompanying mRNA during translation in mammalian cells remain poorly understood. Here, we discovered that YB-1 (YBX1), a major partner of mRNAs in the cytoplasm, forms a linear nucleoprotein filament with mRNA, when part of the YB-1 unstructured C-terminus has been tru...

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Publicado en:Nucleic Acids Res
Autores principales: Kretov, Dmitry A, Clément, Marie-Jeanne, Lambert, Guillaume, Durand, Dominique, Lyabin, Dmitry N, Bollot, Guillaume, Bauvais, Cyril, Samsonova, Anastasiia, Budkina, Karina, Maroun, Rachid C, Hamon, Loic, Bouhss, Ahmed, Lescop, Ewen, Toma, Flavio, Curmi, Patrick A, Maucuer, Alexandre, Ovchinnikov, Lev P, Pastré, David
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2019
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451097/
https://ncbi.nlm.nih.gov/pubmed/30605522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1303
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