The Cold Shock Domain of YB-1 Segregates RNA from DNA by Non-Bonded Interactions

The human YB-1 protein plays multiple cellular roles, of which many are dictated by its binding to RNA and DNA through its Cold Shock Domain (CSD). Using molecular dynamics simulation approaches validated by experimental assays, the YB1 CSD was found to interact with nucleic acids in a sequence-depe...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Kljashtorny, Vladislav, Nikonov, Stanislav, Ovchinnikov, Lev, Lyabin, Dmitry, Vodovar, Nicolas, Curmi, Patrick, Manivet, Philippe
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493011/
https://ncbi.nlm.nih.gov/pubmed/26147853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130318
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