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The Cold Shock Domain of YB-1 Segregates RNA from DNA by Non-Bonded Interactions

The human YB-1 protein plays multiple cellular roles, of which many are dictated by its binding to RNA and DNA through its Cold Shock Domain (CSD). Using molecular dynamics simulation approaches validated by experimental assays, the YB1 CSD was found to interact with nucleic acids in a sequence-depe...

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Pubblicato in:PLoS One
Autori principali: Kljashtorny, Vladislav, Nikonov, Stanislav, Ovchinnikov, Lev, Lyabin, Dmitry, Vodovar, Nicolas, Curmi, Patrick, Manivet, Philippe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493011/
https://ncbi.nlm.nih.gov/pubmed/26147853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130318
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