The Cold Shock Domain of YB-1 Segregates RNA from DNA by Non-Bonded Interactions

The human YB-1 protein plays multiple cellular roles, of which many are dictated by its binding to RNA and DNA through its Cold Shock Domain (CSD). Using molecular dynamics simulation approaches validated by experimental assays, the YB1 CSD was found to interact with nucleic acids in a sequence-depe...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Kljashtorny, Vladislav, Nikonov, Stanislav, Ovchinnikov, Lev, Lyabin, Dmitry, Vodovar, Nicolas, Curmi, Patrick, Manivet, Philippe
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493011/
https://ncbi.nlm.nih.gov/pubmed/26147853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130318
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