Lin28, a major translation reprogramming factor, gains access to YB-1-packaged mRNA through its cold-shock domain

The RNA-binding protein Lin28 (Lin28a) is an important pluripotency factor that reprograms translation and promotes cancer progression. Although Lin28 blocks let-7 microRNA maturation, Lin28 also binds to a large set of cytoplasmic mRNAs directly. However, how Lin28 regulates the processing of many...

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Publié dans:Commun Biol
Auteurs principaux: Samsonova, Anastasiia, El Hage, Krystel, Desforges, Bénédicte, Joshi, Vandana, Clément, Marie-Jeanne, Lambert, Guillaume, Henrie, Hélène, Babault, Nicolas, Craveur, Pierrick, Maroun, Rachid C., Steiner, Emilie, Bouhss, Ahmed, Maucuer, Alexandre, Lyabin, Dmitry N., Ovchinnikov, Lev P., Hamon, Loic, Pastré, David
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979924/
https://ncbi.nlm.nih.gov/pubmed/33742080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01862-3
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