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Lin28, a major translation reprogramming factor, gains access to YB-1-packaged mRNA through its cold-shock domain
The RNA-binding protein Lin28 (Lin28a) is an important pluripotency factor that reprograms translation and promotes cancer progression. Although Lin28 blocks let-7 microRNA maturation, Lin28 also binds to a large set of cytoplasmic mRNAs directly. However, how Lin28 regulates the processing of many...
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| 出版年: | Commun Biol |
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| 主要な著者: | , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2021
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7979924/ https://ncbi.nlm.nih.gov/pubmed/33742080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01862-3 |
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