YB-1, an abundant core mRNA-binding protein, has the capacity to form an RNA nucleoprotein filament: a structural analysis

The structural rearrangements accompanying mRNA during translation in mammalian cells remain poorly understood. Here, we discovered that YB-1 (YBX1), a major partner of mRNAs in the cytoplasm, forms a linear nucleoprotein filament with mRNA, when part of the YB-1 unstructured C-terminus has been tru...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Kretov, Dmitry A, Clément, Marie-Jeanne, Lambert, Guillaume, Durand, Dominique, Lyabin, Dmitry N, Bollot, Guillaume, Bauvais, Cyril, Samsonova, Anastasiia, Budkina, Karina, Maroun, Rachid C, Hamon, Loic, Bouhss, Ahmed, Lescop, Ewen, Toma, Flavio, Curmi, Patrick A, Maucuer, Alexandre, Ovchinnikov, Lev P, Pastré, David
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
RNA and RNA-protein complexes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451097/
https://ncbi.nlm.nih.gov/pubmed/30605522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1303
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