YB-1, an abundant core mRNA-binding protein, has the capacity to form an RNA nucleoprotein filament: a structural analysis

The structural rearrangements accompanying mRNA during translation in mammalian cells remain poorly understood. Here, we discovered that YB-1 (YBX1), a major partner of mRNAs in the cytoplasm, forms a linear nucleoprotein filament with mRNA, when part of the YB-1 unstructured C-terminus has been tru...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Kretov, Dmitry A, Clément, Marie-Jeanne, Lambert, Guillaume, Durand, Dominique, Lyabin, Dmitry N, Bollot, Guillaume, Bauvais, Cyril, Samsonova, Anastasiia, Budkina, Karina, Maroun, Rachid C, Hamon, Loic, Bouhss, Ahmed, Lescop, Ewen, Toma, Flavio, Curmi, Patrick A, Maucuer, Alexandre, Ovchinnikov, Lev P, Pastré, David
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
RNA and RNA-protein complexes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451097/
https://ncbi.nlm.nih.gov/pubmed/30605522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1303
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