YB-1, an abundant core mRNA-binding protein, has the capacity to form an RNA nucleoprotein filament: a structural analysis

The structural rearrangements accompanying mRNA during translation in mammalian cells remain poorly understood. Here, we discovered that YB-1 (YBX1), a major partner of mRNAs in the cytoplasm, forms a linear nucleoprotein filament with mRNA, when part of the YB-1 unstructured C-terminus has been tru...

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發表在:Nucleic Acids Res
Main Authors: Kretov, Dmitry A, Clément, Marie-Jeanne, Lambert, Guillaume, Durand, Dominique, Lyabin, Dmitry N, Bollot, Guillaume, Bauvais, Cyril, Samsonova, Anastasiia, Budkina, Karina, Maroun, Rachid C, Hamon, Loic, Bouhss, Ahmed, Lescop, Ewen, Toma, Flavio, Curmi, Patrick A, Maucuer, Alexandre, Ovchinnikov, Lev P, Pastré, David
格式: Artigo
語言:Inglês
出版: Oxford University Press 2019
主題:
RNA and RNA-protein complexes
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451097/
https://ncbi.nlm.nih.gov/pubmed/30605522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1303
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