YB-1, an abundant core mRNA-binding protein, has the capacity to form an RNA nucleoprotein filament: a structural analysis

The structural rearrangements accompanying mRNA during translation in mammalian cells remain poorly understood. Here, we discovered that YB-1 (YBX1), a major partner of mRNAs in the cytoplasm, forms a linear nucleoprotein filament with mRNA, when part of the YB-1 unstructured C-terminus has been tru...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Kretov, Dmitry A, Clément, Marie-Jeanne, Lambert, Guillaume, Durand, Dominique, Lyabin, Dmitry N, Bollot, Guillaume, Bauvais, Cyril, Samsonova, Anastasiia, Budkina, Karina, Maroun, Rachid C, Hamon, Loic, Bouhss, Ahmed, Lescop, Ewen, Toma, Flavio, Curmi, Patrick A, Maucuer, Alexandre, Ovchinnikov, Lev P, Pastré, David
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
RNA and RNA-protein complexes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451097/
https://ncbi.nlm.nih.gov/pubmed/30605522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1303
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