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The human HOXA9 protein uses paralog-specific residues of the homeodomain to interact with TALE-class cofactors
HOX proteins interact with PBX and MEIS cofactors, which belong to the TALE-class of homeodomain (HD)-containing transcription factors. Although the formation of HOX-PBX complexes depends on a unique conserved HOX motif called hexapeptide (HX), the additional presence of MEIS induces a remodeling of...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6450960/ https://ncbi.nlm.nih.gov/pubmed/30952900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42096-y |
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