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The human HOXA9 protein uses paralog-specific residues of the homeodomain to interact with TALE-class cofactors
HOX proteins interact with PBX and MEIS cofactors, which belong to the TALE-class of homeodomain (HD)-containing transcription factors. Although the formation of HOX-PBX complexes depends on a unique conserved HOX motif called hexapeptide (HX), the additional presence of MEIS induces a remodeling of...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6450960/ https://ncbi.nlm.nih.gov/pubmed/30952900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42096-y |
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