PBX3 is an important cofactor of HOXA9 in leukemogenesis

Although PBX proteins are known to increase DNA-binding/transcriptional activity of HOX proteins through their direct binding, the functional importance of their interaction in leukemogenesis is unclear. We recently reported that overexpression of a 4-homeobox-gene signature (ie, PBX3/HOXA7/HOXA9/HO...

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Hauptverfasser: Li, Zejuan, Zhang, Zhiyu, Li, Yuanyuan, Arnovitz, Stephen, Chen, Ping, Huang, Hao, Jiang, Xi, Hong, Gia-Ming, Kunjamma, Rejani B., Ren, Haomin, He, Chunjiang, Wang, Chong-Zhi, Elkahloun, Abdel G., Valk, Peter J. M., Döhner, Konstanze, Neilly, Mary Beth, Bullinger, Lars, Delwel, Ruud, Löwenberg, Bob, Liu, Paul P., Morgan, Richard, Rowley, Janet D., Yuan, Chun-Su, Chen, Jianjun
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2013
Schlagworte:
Myeloid Neoplasia
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578957/
https://ncbi.nlm.nih.gov/pubmed/23264595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-07-442004
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