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Role of HOXA9 in leukemia: dysregulation, cofactors and essential targets
HOXA9 is a homeodomain-containing transcription factor that plays an important role in hematopoietic stem cell expansion and is commonly deregulated in acute leukemias. A variety of upstream genetic alterations in acute myeloid leukemia (AML) lead to overexpression of HOXA9, which is a strong predic...
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| Publicado no: | Oncogene |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4666810/ https://ncbi.nlm.nih.gov/pubmed/26028034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.174 |
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