C/EBPα is an essential collaborator in Hoxa9/Meis1-mediated leukemogenesis

Homeobox A9 (HOXA9) is a homeodomain-containing transcription factor that plays a key role in hematopoietic stem cell expansion and is commonly deregulated in human acute leukemias. A variety of upstream genetic alterations in acute myeloid leukemia (AML) lead to overexpression of HOXA9, almost alwa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Collins, Cailin, Wang, Jingya, Miao, Hongzhi, Bronstein, Joel, Nawer, Humaira, Xu, Tao, Figueroa, Maria, Muntean, Andrew G., Hess, Jay L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2014
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103350/
https://ncbi.nlm.nih.gov/pubmed/24958854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1402238111
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