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CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein
The HOXA9 homeodomain protein is a key regulator of hematopoiesis and embryonic development. HOXA9 is expressed in primitive hematopoietic cells, and its prompt downregulation is associated with myelocytic maturation. Although transcriptional inactivation of HOXA9 during hematopoietic differentiatio...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2003
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC275435/ https://ncbi.nlm.nih.gov/pubmed/14609952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg577 |
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