Systematic characterization of the HOXA9 downstream targets in MLL-r leukemia by noncoding CRISPR screens
Abstract Accumulating evidence indicates that HOXA9 dysregulation is necessary and sufficient for leukemic transformation and maintenance. However, it remains largely unknown how HOXA9, as a homeobox transcriptional factor, binds to noncoding regulatory sequences and controls the downstream genes. H...
Furkejuvvon:
| Váldodahkkit: | , , , , , , , , , , |
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| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
Nature Portfolio
2023-11-01
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| Ráidu: | Nature Communications |
| Liŋkkat: | https://doi.org/10.1038/s41467-023-43264-5 |
| Fáddágilkorat: |
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