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CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein

The HOXA9 homeodomain protein is a key regulator of hematopoiesis and embryonic development. HOXA9 is expressed in primitive hematopoietic cells, and its prompt downregulation is associated with myelocytic maturation. Although transcriptional inactivation of HOXA9 during hematopoietic differentiatio...

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Bibliografske podrobnosti
izdano v:EMBO J
Principais autores: Zhang, Yue, Morrone, Giovanni, Zhang, Jianxuan, Chen, Xiaoai, Lu, Xiaoling, Ma, Liang, Moore, Malcolm, Zhou, Pengbo
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2003
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275435/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14609952/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg577
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