CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein

The HOXA9 homeodomain protein is a key regulator of hematopoiesis and embryonic development. HOXA9 is expressed in primitive hematopoietic cells, and its prompt downregulation is associated with myelocytic maturation. Although transcriptional inactivation of HOXA9 during hematopoietic differentiatio...

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Bibliografiske detaljer
Main Authors: Zhang, Yue, Morrone, Giovanni, Zhang, Jianxuan, Chen, Xiaoai, Lu, Xiaoling, Ma, Liang, Moore, Malcolm, Zhou, Pengbo
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC275435/
https://ncbi.nlm.nih.gov/pubmed/14609952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg577
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