Rational Design of Antiangiogenic Helical Oligopeptides Targeting the Vascular Endothelial Growth Factor Receptors

Tumor angiogenesis, essential for cancer development, is regulated mainly by vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs), which are overexpressed in cancer cells. Therefore, the VEGF/VEGFR interaction represents a promising pharmaceutical target to fight cancer progressi...

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Dades bibliogràfiques
Publicat a:Front Chem
Autors principals: Zanella, Simone, Bocchinfuso, Gianfranco, De Zotti, Marta, Arosio, Daniela, Marino, Franca, Raniolo, Stefano, Pignataro, Luca, Sacco, Giovanni, Palleschi, Antonio, Siano, Alvaro S., Piarulli, Umberto, Belvisi, Laura, Formaggio, Fernando, Gennari, Cesare, Stella, Lorenzo
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Chemistry
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449863/
https://ncbi.nlm.nih.gov/pubmed/30984741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00170
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