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Investigating the Interaction of Cyclic RGD Peptidomimetics with α(V)β(6) Integrin by Biochemical and Molecular Docking Studies

The interaction of a small library of cyclic RGD (Arg-Gly-Asp) peptidomimetics with α(V)β(6) integrin has been investigated by means of competitive solid phase binding assays to the isolated receptor and docking calculations in the crystal structure of the α(V)β(6) binding site. To this aim, a rigid...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Civera, Monica, Arosio, Daniela, Bonato, Francesca, Manzoni, Leonardo, Pignataro, Luca, Zanella, Simone, Gennari, Cesare, Piarulli, Umberto, Belvisi, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664067/
https://ncbi.nlm.nih.gov/pubmed/28934103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers9100128
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