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Investigating the Interaction of Cyclic RGD Peptidomimetics with α(V)β(6) Integrin by Biochemical and Molecular Docking Studies

The interaction of a small library of cyclic RGD (Arg-Gly-Asp) peptidomimetics with α(V)β(6) integrin has been investigated by means of competitive solid phase binding assays to the isolated receptor and docking calculations in the crystal structure of the α(V)β(6) binding site. To this aim, a rigid...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Civera, Monica, Arosio, Daniela, Bonato, Francesca, Manzoni, Leonardo, Pignataro, Luca, Zanella, Simone, Gennari, Cesare, Piarulli, Umberto, Belvisi, Laura
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664067/
https://ncbi.nlm.nih.gov/pubmed/28934103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers9100128
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