Insights into the Binding of Cyclic RGD Peptidomimetics to α(5)β(1) Integrin by using Live‐Cell NMR And Computational Studies

The interaction of a small library of cyclic DKP–RGD peptidomimetics with α(5)β(1) integrin has been investigated by means of an integrated experimental and computational approach. Bioaffinity NMR techniques, including saturation transfer difference (STD) and transferred NOESY, were applied to the l...

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Detalhes bibliográficos
Publicado no:ChemistryOpen
Main Authors: Guzzetti, Ileana, Civera, Monica, Vasile, Francesca, Arosio, Daniela, Tringali, Cristina, Piarulli, Umberto, Gennari, Cesare, Pignataro, Luca, Belvisi, Laura, Potenza, Donatella
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Full Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288746/
https://ncbi.nlm.nih.gov/pubmed/28168158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201600112
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