Insights into the Binding of Cyclic RGD Peptidomimetics to α(5)β(1) Integrin by using Live‐Cell NMR And Computational Studies

The interaction of a small library of cyclic DKP–RGD peptidomimetics with α(5)β(1) integrin has been investigated by means of an integrated experimental and computational approach. Bioaffinity NMR techniques, including saturation transfer difference (STD) and transferred NOESY, were applied to the l...

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Vydáno v:ChemistryOpen
Hlavní autoři: Guzzetti, Ileana, Civera, Monica, Vasile, Francesca, Arosio, Daniela, Tringali, Cristina, Piarulli, Umberto, Gennari, Cesare, Pignataro, Luca, Belvisi, Laura, Potenza, Donatella
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288746/
https://ncbi.nlm.nih.gov/pubmed/28168158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201600112
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