Insights into the Binding of Cyclic RGD Peptidomimetics to α(5)β(1) Integrin by using Live‐Cell NMR And Computational Studies

The interaction of a small library of cyclic DKP–RGD peptidomimetics with α(5)β(1) integrin has been investigated by means of an integrated experimental and computational approach. Bioaffinity NMR techniques, including saturation transfer difference (STD) and transferred NOESY, were applied to the l...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:ChemistryOpen
Prif Awduron: Guzzetti, Ileana, Civera, Monica, Vasile, Francesca, Arosio, Daniela, Tringali, Cristina, Piarulli, Umberto, Gennari, Cesare, Pignataro, Luca, Belvisi, Laura, Potenza, Donatella
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2016
Pynciau:
Full Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288746/
https://ncbi.nlm.nih.gov/pubmed/28168158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201600112
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