Insights into the Binding of Cyclic RGD Peptidomimetics to α(5)β(1) Integrin by using Live‐Cell NMR And Computational Studies

The interaction of a small library of cyclic DKP–RGD peptidomimetics with α(5)β(1) integrin has been investigated by means of an integrated experimental and computational approach. Bioaffinity NMR techniques, including saturation transfer difference (STD) and transferred NOESY, were applied to the l...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:ChemistryOpen
Main Authors: Guzzetti, Ileana, Civera, Monica, Vasile, Francesca, Arosio, Daniela, Tringali, Cristina, Piarulli, Umberto, Gennari, Cesare, Pignataro, Luca, Belvisi, Laura, Potenza, Donatella
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Full Papers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288746/
https://ncbi.nlm.nih.gov/pubmed/28168158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201600112
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