Rational Design of Antiangiogenic Helical Oligopeptides Targeting the Vascular Endothelial Growth Factor Receptors

Tumor angiogenesis, essential for cancer development, is regulated mainly by vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs), which are overexpressed in cancer cells. Therefore, the VEGF/VEGFR interaction represents a promising pharmaceutical target to fight cancer progressi...

詳細記述

保存先:
書誌詳細
出版年:Front Chem
主要な著者: Zanella, Simone, Bocchinfuso, Gianfranco, De Zotti, Marta, Arosio, Daniela, Marino, Franca, Raniolo, Stefano, Pignataro, Luca, Sacco, Giovanni, Palleschi, Antonio, Siano, Alvaro S., Piarulli, Umberto, Belvisi, Laura, Formaggio, Fernando, Gennari, Cesare, Stella, Lorenzo
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2019
主題:
Chemistry
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449863/
https://ncbi.nlm.nih.gov/pubmed/30984741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00170
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