Rational Design of Antiangiogenic Helical Oligopeptides Targeting the Vascular Endothelial Growth Factor Receptors

Tumor angiogenesis, essential for cancer development, is regulated mainly by vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs), which are overexpressed in cancer cells. Therefore, the VEGF/VEGFR interaction represents a promising pharmaceutical target to fight cancer progressi...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Chem
Main Authors: Zanella, Simone, Bocchinfuso, Gianfranco, De Zotti, Marta, Arosio, Daniela, Marino, Franca, Raniolo, Stefano, Pignataro, Luca, Sacco, Giovanni, Palleschi, Antonio, Siano, Alvaro S., Piarulli, Umberto, Belvisi, Laura, Formaggio, Fernando, Gennari, Cesare, Stella, Lorenzo
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Chemistry
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449863/
https://ncbi.nlm.nih.gov/pubmed/30984741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00170
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