Generation of single-copy transgenic mouse embryos directly from ES cells by tetraploid embryo complementation

BACKGROUND: Transgenic mice have been used extensively to analyze gene function. Unfortunately, traditional transgenic procedures have only limited use in analyzing alleles that cause lethality because lines of founder mice cannot be established. This is frustrating given that such alleles often rev...

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Библиографические подробности

Опубликовано в::	BMC Biotechnol
Главные авторы:	Misra, Ravi P, Bronson, Sarah K, Xiao, Qi, Garrison, Wendy, Li, Jixuan, Zhao, Roong, Duncan, Stephen A
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2001
Предметы:	Methodology Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC64498/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11782291/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1472-6750-1-12
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