Generation of single-copy transgenic mouse embryos directly from ES cells by tetraploid embryo complementation

BACKGROUND: Transgenic mice have been used extensively to analyze gene function. Unfortunately, traditional transgenic procedures have only limited use in analyzing alleles that cause lethality because lines of founder mice cannot be established. This is frustrating given that such alleles often rev...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Misra, Ravi P, Bronson, Sarah K, Xiao, Qi, Garrison, Wendy, Li, Jixuan, Zhao, Roong, Duncan, Stephen A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2001
Pynciau:
Methodology Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC64498/
https://ncbi.nlm.nih.gov/pubmed/11782291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-1-12
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