Generation of single-copy transgenic mouse embryos directly from ES cells by tetraploid embryo complementation

BACKGROUND: Transgenic mice have been used extensively to analyze gene function. Unfortunately, traditional transgenic procedures have only limited use in analyzing alleles that cause lethality because lines of founder mice cannot be established. This is frustrating given that such alleles often rev...

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Detaylı Bibliyografya
Asıl Yazarlar: Misra, Ravi P, Bronson, Sarah K, Xiao, Qi, Garrison, Wendy, Li, Jixuan, Zhao, Roong, Duncan, Stephen A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2001
Konular:
Methodology Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC64498/
https://ncbi.nlm.nih.gov/pubmed/11782291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-1-12
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