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N,N-Dimethylaminoxy Carbonyl, a Polar Protecting Group for Efficient Peptide Synthesis

Peptide coupling with minimal protection is one of the desired methods for the synthesis of peptides and proteins. To achieve regioselective amide bond formation, side chain protection is often essential; however, protecting groups potentially diminish peptide solubility and render the polar polyami...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Okamoto, Ryo, Ono, Emiko, Izumi, Masayuki, Kajihara, Yasuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447706/
https://ncbi.nlm.nih.gov/pubmed/30984743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00173
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