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N,N-Dimethylaminoxy Carbonyl, a Polar Protecting Group for Efficient Peptide Synthesis

Peptide coupling with minimal protection is one of the desired methods for the synthesis of peptides and proteins. To achieve regioselective amide bond formation, side chain protection is often essential; however, protecting groups potentially diminish peptide solubility and render the polar polyami...

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Publicat a:Front Chem
Autors principals: Okamoto, Ryo, Ono, Emiko, Izumi, Masayuki, Kajihara, Yasuhiro
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447706/
https://ncbi.nlm.nih.gov/pubmed/30984743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00173
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