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Intimate Interactions with Carbonyl Groups: Dipole–Dipole or n→π*?

Amide carbonyl groups in proteins can engage in C=O···C=O and C–X···C=O interactions, where X is a halogen. The putative involvement of four poles suggests that these interactions are primarily dipolar. Our survey of crystal structures with a C–X···C=O contact that is short (i.e., within the sum of...

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Autors principals: Kamer, Kimberli J., Choudhary, Amit, Raines, Ronald T.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586291/
https://ncbi.nlm.nih.gov/pubmed/23163960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo302265k
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