cGAS facilitates sensing of extracellular cyclic dinucleotides to activate innate immunity

Cyclic dinucleotides (CDNs) are important second messenger molecules in prokaryotes and eukaryotes. Within host cells, cytosolic CDNs are detected by STING and alert the host by activating innate immunity characterized by type I interferon (IFN) responses. Extracellular bacteria and dying cells can...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Liu, Haipeng, Moura‐Alves, Pedro, Pei, Gang, Mollenkopf, Hans‐Joachim, Hurwitz, Robert, Wu, Xiangyang, Wang, Fei, Liu, Siyu, Ma, Mingtong, Fei, Yiyan, Zhu, Chenggang, Koehler, Anne‐Britta, Oberbeck‐Mueller, Dagmar, Hahnke, Karin, Klemm, Marion, Guhlich‐Bornhof, Ute, Ge, Baoxue, Tuukkanen, Anne, Kolbe, Michael, Dorhoi, Anca, Kaufmann, Stefan HE
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446192/
https://ncbi.nlm.nih.gov/pubmed/30872316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201846293
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados