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Synthesis of an acridine orange sulfonamide derivative with potent carbonic anhydrase IX inhibitory action

Acridine orange (AO) a fluorescent cationic dye used for the management of human musculoskeletal sarcomas, due to its strong tumoricidal action and accumulation in the acidic environment typical of hypoxic tumors, was used for the preparation of a primary sulfonamide derivative. The rationale behind...

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Detaylı Bibliyografya
Yayımlandı:J Enzyme Inhib Med Chem
Asıl Yazarlar: Bragagni, Marco, Carta, Fabrizio, Osman, Sameh M., AlOthman, Zeid, Supuran, Claudiu T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445237/
https://ncbi.nlm.nih.gov/pubmed/28335646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1302441
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