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Sulfonamides with Potent Inhibitory Action and Selectivity against the α-Carbonic Anhydrase from Vibrio cholerae

[Image: see text] By using N-α-acetyl-l-lysine or GABA scaffolds and the conversion of the terminal amino group to the guanidine one, benzenesulfonamides incorporating water solubilizing moieties were synthesized. The new compounds were medium potency inhibitors of the cytosolic carbonic anhydrase (...

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Detaylı Bibliyografya
Asıl Yazarlar: Ceruso, Mariangela, Del Prete, Sonia, Alothman, Zeid, Capasso, Clemente, Supuran, Claudiu T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2014
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094250/
https://ncbi.nlm.nih.gov/pubmed/25050173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500192a
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