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Carbonic anhydrase I, II, IV and IX inhibition with a series of 7-amino-3,4-dihydroquinolin-2(1H)-one derivatives

A series of new derivatives was prepared by derivatisation of the 7-amino moiety present in 7-amino-3,4-dihydroquinolin-2(1H)-one, a compound investigated earlier as CAI. The derivatisation was achieved by: i) reaction with arylsulfonyl isocyanates/aryl isocyanates; (ii) reaction with fluorescein is...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Bozdag, Murat, Bua, Silvia, Osman, Sameh M., AlOthman, Zeid, Supuran, Claudiu T.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445181/
https://ncbi.nlm.nih.gov/pubmed/28644059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1337759
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