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Synthesis of an acridine orange sulfonamide derivative with potent carbonic anhydrase IX inhibitory action

Acridine orange (AO) a fluorescent cationic dye used for the management of human musculoskeletal sarcomas, due to its strong tumoricidal action and accumulation in the acidic environment typical of hypoxic tumors, was used for the preparation of a primary sulfonamide derivative. The rationale behind...

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書目詳細資料
發表在:J Enzyme Inhib Med Chem
Main Authors: Bragagni, Marco, Carta, Fabrizio, Osman, Sameh M., AlOthman, Zeid, Supuran, Claudiu T.
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445237/
https://ncbi.nlm.nih.gov/pubmed/28335646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1302441
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