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Synthesis of an acridine orange sulfonamide derivative with potent carbonic anhydrase IX inhibitory action

Acridine orange (AO) a fluorescent cationic dye used for the management of human musculoskeletal sarcomas, due to its strong tumoricidal action and accumulation in the acidic environment typical of hypoxic tumors, was used for the preparation of a primary sulfonamide derivative. The rationale behind...

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Bibliografske podrobnosti
izdano v:J Enzyme Inhib Med Chem
Main Authors: Bragagni, Marco, Carta, Fabrizio, Osman, Sameh M., AlOthman, Zeid, Supuran, Claudiu T.
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445237/
https://ncbi.nlm.nih.gov/pubmed/28335646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1302441
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