Wird geladen...
Adamantyl thioureas as soluble epoxide hydrolase inhibitors
A series of inhibitors of the soluble epoxide hydrolase (sEH) containing one or two thiourea groups has been developed. Inhibition potency of the described compounds ranges from 50 μM to 7.2 nM. 1,7-(Heptamethylene)bis[(adamant-1-yl)thiourea] (6f) was found to be the most potent sEH inhibitor, among...
Gespeichert in:
| Veröffentlicht in: | Bioorg Med Chem Lett |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6442743/ https://ncbi.nlm.nih.gov/pubmed/29803731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2018.05.024 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|