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Structure of the Transition State of Gating in the Acetylcholine Receptor Channel Pore: A Φ-Value Analysis

The gating mechanism of the acetylcholine receptor channel (AChR) was investigated by using rate equilibrium linear free energy relationships (LFERs) to probe the transition state between the closed and open conformations. The properties of the transition state of gating in the second transmembrane...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Cymes, Gisela D., Grosman, Claudio, Auerbach, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442467/
https://ncbi.nlm.nih.gov/pubmed/11969415
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