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Structure of the Transition State of Gating in the Acetylcholine Receptor Channel Pore: A Φ-Value Analysis

The gating mechanism of the acetylcholine receptor channel (AChR) was investigated by using rate equilibrium linear free energy relationships (LFERs) to probe the transition state between the closed and open conformations. The properties of the transition state of gating in the second transmembrane...

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Publicado en:Biochemistry
Autores principales: Cymes, Gisela D., Grosman, Claudio, Auerbach, Anthony
Formato: Artigo
Lenguaje:Inglês
Publicado: 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442467/
https://ncbi.nlm.nih.gov/pubmed/11969415
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