Nalaganje...
Kinetic, Mechanistic, and Structural Aspects of Unliganded Gating of Acetylcholine Receptor Channels: A Single-Channel Study of Second Transmembrane Segment 12′ Mutants
The spontaneous activity of adult mouse muscle acetylcholine receptor channels, transiently expressed in HEK-293 cells, was studied with the patch-clamp technique. To increase the frequency of unliganded openings, mutations at the 12′ position of the second transmembrane segment were engineered. Our...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2000
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2217228/ https://ncbi.nlm.nih.gov/pubmed/10779319 |
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