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Structure of the Transition State of Gating in the Acetylcholine Receptor Channel Pore: A Φ-Value Analysis

The gating mechanism of the acetylcholine receptor channel (AChR) was investigated by using rate equilibrium linear free energy relationships (LFERs) to probe the transition state between the closed and open conformations. The properties of the transition state of gating in the second transmembrane...

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Publicat a:Biochemistry
Autors principals: Cymes, Gisela D., Grosman, Claudio, Auerbach, Anthony
Format: Artigo
Idioma:Inglês
Publicat: 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442467/
https://ncbi.nlm.nih.gov/pubmed/11969415
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