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Pore-opening mechanism of the nicotinic acetylcholine receptor evinced by proton transfer

The conformational changes underlying Cys-loop receptor channel gating remain elusive and controversial. We previously developed a single-channel electrophysiological method that allows structural inferences about the transient open-channel conformation to be made from the effect and properties of i...

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Detalhes bibliográficos
Main Authors: Cymes, Gisela D, Grosman, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596065/
https://ncbi.nlm.nih.gov/pubmed/18376414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1407
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