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Tunable pK(a) values and the basis of opposite charge selectivities in nicotinic-type receptors

Among ion channels, only the nicotinic-receptor superfamily has evolved to generate both cation- and anion-selective members. Although other, structurally unrelated, neurotransmitter-gated cation channels exist, no other type of neurotransmitter-gated anion channel, and thus no other source of fast...

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Detalhes bibliográficos
Main Authors: Cymes, Gisela D., Grosman, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121909/
https://ncbi.nlm.nih.gov/pubmed/21602825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10015
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