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Tunable pK(a) values and the basis of opposite charge selectivities in nicotinic-type receptors

Among ion channels, only the nicotinic-receptor superfamily has evolved to generate both cation- and anion-selective members. Although other, structurally unrelated, neurotransmitter-gated cation channels exist, no other type of neurotransmitter-gated anion channel, and thus no other source of fast...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cymes, Gisela D., Grosman, Claudio
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121909/
https://ncbi.nlm.nih.gov/pubmed/21602825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10015
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