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Dynamics of the acetylcholine receptor pore at the gating transition state

Neuromuscular acetylcholine receptors (AChRs) are ion channels that alternatively adopt stable conformations that either allow (open) or prohibit (closed) ionic conduction. We probed the dynamics of pore (M2) residues at the diliganded gating transition state by using single-channel kinetic and rate...

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Detalhes bibliográficos
Main Authors: Mitra, Ananya, Cymes, Gisela D., Auerbach, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1257706/
https://ncbi.nlm.nih.gov/pubmed/16217024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505090102
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