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Plasticity of Acetylcholine Receptor Gating Motions via Rate-Energy Relationships

Like other protein conformational changes, ion channel gating requires the protein to achieve a high-energy transition-state structure. It is not known whether ion channel gating takes place on a broad energy landscape on which many alternative transition state structures are accessible, or on a nar...

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Autori principali: Mitra, Ananya, Tascione, Richard, Auerbach, Anthony, Licht, Stuart
Natura: Artigo
Lingua:Inglês
Pubblicazione: Biophysical Society 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366804/
https://ncbi.nlm.nih.gov/pubmed/16113115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.068783
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