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Gating of acetylcholine receptor channels: Brownian motion across a broad transition state

Acetylcholine receptor channels (AChRs) are proteins that switch between stable “closed” and “open” conformations. In patch clamp recordings, diliganded AChR gating appears to be a simple, two-state reaction. However, mutagenesis studies indicate that during gating dozens of residues across the prot...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awdur: Auerbach, Anthony
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2005
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC547815/
https://ncbi.nlm.nih.gov/pubmed/15665102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406787102
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