TET2 binding to enhancers facilitates transcription factor recruitment in hematopoietic cells

The epigenetic regulator TET2 is frequently mutated in hematological diseases. Mutations have been shown to arise in hematopoietic stem cells early in disease development and lead to altered DNA methylation landscapes and an increased risk of hematopoietic malignancy. Here, we show by genome-wide ma...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Genome Res
मुख्य लेखकों: Rasmussen, Kasper D., Berest, Ivan, Keβler, Sandra, Nishimura, Koutarou, Simón-Carrasco, Lucía, Vassiliou, George S., Pedersen, Marianne T., Christensen, Jesper, Zaugg, Judith B., Helin, Kristian
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Cold Spring Harbor Laboratory Press 2019
विषय:
Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442383/
https://ncbi.nlm.nih.gov/pubmed/30796038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.239277.118
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