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Role of TET enzymes in DNA methylation, development, and cancer
The pattern of DNA methylation at cytosine bases in the genome is tightly linked to gene expression, and DNA methylation abnormalities are often observed in diseases. The ten eleven translocation (TET) enzymes oxidize 5-methylcytosines (5mCs) and promote locus-specific reversal of DNA methylation. T...
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| Опубликовано в: : | Genes Dev |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4826392/ https://ncbi.nlm.nih.gov/pubmed/27036965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.276568.115 |
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