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Role of TET enzymes in DNA methylation, development, and cancer

The pattern of DNA methylation at cytosine bases in the genome is tightly linked to gene expression, and DNA methylation abnormalities are often observed in diseases. The ten eleven translocation (TET) enzymes oxidize 5-methylcytosines (5mCs) and promote locus-specific reversal of DNA methylation. T...

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Bibliografski detalji
Izdano u:Genes Dev
Glavni autori: Rasmussen, Kasper Dindler, Helin, Kristian
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826392/
https://ncbi.nlm.nih.gov/pubmed/27036965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.276568.115
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