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EGFR and Prion protein promote signaling via FOXO3a‐KLF5 resulting in clinical resistance to platinum agents in colorectal cancer
Epidermal growth factor receptor (EGFR) supports colorectal cancer progression via oncogenic signaling. Anti‐EGFR therapy is being investigated as a clinical option for colorectal cancer, and an observed interaction between EGFR and Prion protein has been detected in neuronal cells. We hypothesized...
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| Publicado no: | Mol Oncol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6441932/ https://ncbi.nlm.nih.gov/pubmed/30478887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12411 |
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