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Potential roles for prions and protein-only inheritance in cancer

Inherited mutations are known to cause familial cancers. However, the cause of sporadic cancers, which likely represent the majority of cancers, is yet to be elucidated. Sporadic cancers contain somatic mutations (including oncogenic mutations), however, the origin of these mutations is unclear. An...

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Detalhes bibliográficos
Main Authors: Antony, H, Wiegmans, AP, Wei, MQ, Chernoff, YO, Khanna, KK, Munn, AL
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315606/
https://ncbi.nlm.nih.gov/pubmed/22138778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-011-9325-9
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