EGFR and Prion protein promote signaling via FOXO3a‐KLF5 resulting in clinical resistance to platinum agents in colorectal cancer

Epidermal growth factor receptor (EGFR) supports colorectal cancer progression via oncogenic signaling. Anti‐EGFR therapy is being investigated as a clinical option for colorectal cancer, and an observed interaction between EGFR and Prion protein has been detected in neuronal cells. We hypothesized...

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Bibliographic Details
Published in:Mol Oncol
Main Authors: Atkinson, Caroline J., Kawamata, Futoshi, Liu, Cheng, Ham, Sunyoung, Győrffy, Balázs, Munn, Alan L., Wei, Ming Q., Möller, Andreas, Whitehall, Vicki, Wiegmans, Adrian P.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441932/
https://ncbi.nlm.nih.gov/pubmed/30478887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12411
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