Ursodeoxycholic acid ameliorates hepatic lipid metabolism in LO2 cells by regulating the AKT/mTOR/SREBP-1 signaling pathway

BACKGROUND: Nonalcoholic fatty liver disease (NAFLD), the most common chronic liver disease, can progress into nonalcoholic steatohepatitis (NASH), cirrhosis, and even hepatocellular carcinoma. Bile acids such as ursodeoxycholic acid (UDCA) play an essential role in the pathogenesis of NAFLD by regu...

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Dades bibliogràfiques
Publicat a:World J Gastroenterol
Autors principals: Hu, Jie, Hong, Wei, Yao, Kan-Nan, Zhu, Xiao-Hong, Chen, Zhi-Yun, Ye, Lei
Format: Artigo
Idioma:Inglês
Publicat: Baishideng Publishing Group Inc 2019
Matèries:
Basic Study
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441910/
https://ncbi.nlm.nih.gov/pubmed/30948912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v25.i12.1492
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